There are four main types of cell-cell junctions:
- occluding junctions (zonula occludens or tight junctions)
- adhering junctions (zonula adherens).
- desmosomes (macula adherens). There are also 'hemidesmosomes' that lie on the basal membrane, to help stick the cells to the underlying basal lamina.
- Gap junctions. These are communicating junctions
Adherens Junction. The adheren junction is initiates and maintains cell to cell adhesion, regulates the organization of the underlying action cytoskeleton, and establishes a hub for cell signaling and regulation of gene transcription.